How plant defense chemicals may trigger autoimmunity. Is Nicotinamide Riboside BS? Is spirulina BS?

Throughout my training and practice as a physician, I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.

Time Stamps:

00:10:57 Podcast begins

00:13:53 Paul’s framework and the hierarchy of the optimal human diet

00:19:00 Plant defense chemicals

00:19:44 Non-protein amino acids

00:34:14 Clip of Ben Patrick on The Joe Rogan Experience talking about plant defense chemicals

00:39:05 Joe Rogan clip ends

00:39:20 Hormetic properties of plant chemicals

00:43:33 Deep dive on non-protein amino acids

00:45:40 Link between plant toxins and multiple sclerosis

00:50:50 Link between non-protein amino acids and autoimmunity 

1:00:00 Is algae BS?

1:04:08 Defense chemicals in seaweed

1:05:42 How to optimize cellular NAD levels

1:14:25 Why you do not need to take supplements (NR and NMN)


Heart & Soil: 

White Oak Pastures:, use code CarnivoreMD for 10% off your first order

IceBarrel:, use code PAUL for $125 off

Lets Get Checked: 20% off your order at

Aura: 40% off your first order at

back to podcasts